Specifications
Immunogen
Full length native protein (purified) corresponding to Sheep ATP1A2. Puified from Sheep Kidney.
Applications
Application Notes
WB: 1/500. Detects a band of approximately 102 kDa (predicted molecular weight: 114 kDa).
ICC/IF: 1/20.
Inhibition Assay: Use at an assay dependent concentration;
ICC: Use at an assay dependent concentration;
Flow Cyt: 1/100;
Target
Alternative Names
ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide; sodium/potassium-transporting ATPase subunit alpha-2; sodium pump subunit alpha-2; Na(+)/K(+) ATPase alpha-2 subunit; Na(+)/K(+) ATPase alpha(+) subunit; Atpa-3; AW060654; mKIAA0778;
Product Background
Antigen Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
Citations
Publication ()
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COA
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