Specifications
Immunogen
Other Immunogen Type corresponding to Sheep alpha 1 Sodium Potassium ATPase. Lamb kidney alpha 1 sodium/potassium ATPase.
Applications
Application Notes
IHC-Fr: 1/100;
WB: 1/250. Detects a band of approximately 100 kDa (predicted molecular weight: 110 kDa);
IHC-P: 1/100 - 1/2000.
Inhibition Assay: Use at an assay dependent concentration.
ICC: 1/50 - 1/200.
ELISA: 1/40.
Target
Alternative Names
ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide; sodium/potassium-transporting ATPase subunit alpha-1; sodium pump subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; Atpa-1; BC010319; MGC38419;
Product Background
Antigen Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
Citations
Publication ()
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COA
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