Specifications
Species Reactivity
Human; Mouse; Rat; Dog; Chicken; Pig
Immunogen
Full length native protein (purified) corresponding to Rat alpha 1 Sodium Potassium ATPase. Purified rat kidney sodium/potassium ATPase.
Applications
Application Notes
IHC-P: 1/100; IHC/IF: 1/10 - 1/100; Flow Cyt: 1/50.
Target
Alternative Names
ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide; sodium/potassium-transporting ATPase subunit alpha-1; sodium pump subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; ATPase, Na+K+ transporting, alpha 1; Nkaa1b;
Product Background
Antigen Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
Citations
Publication ()
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COA
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