Anti-ATG4C monoclonal antibody

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to C-terminus of human ATG4C.

Conjugate

Application Notes

ELISA (1:5000-1:20000); WB (1:100-1:2000) & The optimal working dilution should be determined by the end user.

Alternative Names

ATG4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C (S. cerevisiae) , APG4C, AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae) , AUTL1; cysteine protease ATG4C; AUTL3;

Entrez Gene ID

UniProt ID

Antigen Description

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Pathway

Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem;