Anti-APPBP2 monoclonal antibody (DCABH-10570) Made to order

Rabbit anti-Human APPBP2 monoclonal antibody for WB, ELISA

View other APPBP2 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human APPBP2 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
APPBP2; amyloid beta precursor protein (cytoplasmic tail) binding protein 2; amyloid protein-binding protein 2; Hs.84084; KIAA0228; PAT1
Entrez Gene ID
UniProt ID

Product Background


Gene summary
APPBP2 (Amyloid Beta Precursor Protein Binding Protein 2) is a Protein Coding gene. Among its related pathways are Regulation of Androgen receptor activity. GO annotations related to this gene include microtubule motor activity. The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants.
Antigen Description
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimers disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene. 0The function about APPBP2 antigen include microtubule motor activity; protein binding.
Pathway
Regulation of Androgen receptor activity, organism-specific biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Reynard, LN; Cocquet, J; et al. The Multi-Copy Mouse Gene Sycp3-Like Y-Linked (Sly) Encodes an Abundant Spermatid Protein That Interacts with a Histone Acetyltransferase and an Acrosomal Protein. BIOLOGY OF REPRODUCTION 81:250-257(2009).

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