The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function
microtubule motor activity; protein binding
Synonyms
APPBP2; amyloid beta precursor protein (cytoplasmic tail) binding protein 2; PAT1; APP-BP2; HS.84084; amyloid protein-binding protein 2; protein interacting with APP tail 1
Citations
Publication ()
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