General Notes
This product (Catalog No. DPABH-25325) is a rabbit-derived polyclonal antibody raised against human ACLY, targeting the amino acid region 495–1092 of the protein. It has been affinity purified by Protein A. ATP citrate synthase, also known as ATP citrate lyase (ACLY; EC 2.3.3.8), is a cytosolic homotetrameric enzyme that catalyzes the ATP- and CoA-dependent cleavage of citrate to generate acetyl-CoA and oxaloacetate, accompanied by the hydrolysis of ATP to ADP and inorganic phosphate. This reaction serves as the primary mechanism for producing cytosolic acetyl-CoA from mitochondrial-derived citrate, linking carbohydrate metabolism to downstream biosynthetic processes.
DPABH-25325 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-25325 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
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