Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Thr447 and Ser451 of human ATP-citrate (pro-S) lyase.
Applications
Application Notes
WB: 1/1000; ICC/IF: 1/100 - 1/250; IP: 1/10 - 1/100
Target
Alternative Names
ACLY; ATP citrate lyase; ATP-citrate synthase; ACL; ATP citrate synthase; ATPCL; CLATP; citrate cleavage enzyme; ATP-citrate (pro-S-)-lyase;
Product Background
Antigen Description
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Pathway
ChREBP activates metabolic gene expression, organism-specific biosystem; Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-9114 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
