Human Ultra Sensitive C-peptide ELISA Kit

Sample

serum, plasma

Intended Use

This ultra-sensitive C-peptide ELISA kit is intended for use in the quantitative determination of low pico gram level of human connecting peptide in serum or plasma.

Storage

2-8°C

Precision

Sensitivity

0.57 pg/mL.

General Description

C-peptide is a small 31-amino acid peptide usually produced in the pancreas as a byproduct of the cleavage of proinsulin in the synthesis of insulin. Proinsulin consists of A and B chain and connecting peptide in the middle, called C-peptide. It is generally found in equimolar amounts to insulin in circulation. Since the half- life of C-peptide is 3-4 times that of insulin, it serves as a useful measure of insulin production in the beta cells of the pancreas. Testing for C-peptide levels can help find the cause of low blood sugar (hypoglycemia) aid in distinguishing type 1 from type 2 diabetes. A person with diabetes may have a normal level of C- peptide which indicates the body is making plenty of insulin but the body is just not responding properly to it. This is the hallmark of type 2 diabetes (adult insulin-resistant diabetes). Some studies have suggested that C-peptide may have chemotactic effects on the inflammatory cells and might have a role in increased risk of atherosclerosis in persons with type-2 diabetes.