Recombinant Human CKMM [His]

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

44.1 kDa

Purity

> 95% as determined by SDS-PAGE

Format

Liquid

Buffer

20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH7.5

Preservative

None

Storage

Store at -20°C

Introduction

Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.

Keywords

CKMM; Creatine kinase MM