Anti-CK-MM monoclonal antibody (DMAB2205MH)

Mouse anti-Human FGFR3 monoclonal antibody for WB, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
A027-17186
Species Reactivity
Human
Immunogen
Purified human CK-MM
Conjugate
Unconjugated

Target


Alternative Names
CKMM; M-CK; CKM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. The function about CK-MM antigen include ATP binding; creatine kinase activity; nucleotide binding.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem; Urea cycle and metabolism of amino groups, organism-specific biosystem; creatine-phosphate biosynthesis, conserved biosystem.

Citations


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References


HASHIMOTO, H; ABENDSCHEIN, DR; et al. EARLY DETECTION AND TIMING OF MYOCARDIAL-INFARCTION USING PLASMA CREATINE-KINASE (CK) MM ISOFORMS. JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION 49:869-869(1985).
Wang, YM; Zhang, Y; et al. Rhabdomyolysis following recent severe Coxsackie virus infection in patient with chronic renal failure: One case report and a review of the literature. RENAL FAILURE 28:89-93(2006).

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