Product Overview
Recombinant human cardiac troponin IC-complex is a single, non-glycosylated, polypeptide chain. The molar ratio on cTnI to cTnC is 1:1
Alternative Names
Troponin C-I complex; Troponin IC; TNNC; cTnC; cTnI
Purity
> 90% as determined by SDS-PAGE
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
500mM NaCl, 20mM Tris-HCl, 4mM CaCl2, 4mM MgCl2 and 60mM β-mercaptoethanol, pH 7.5.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Introduction
Troponin complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. Troponin complex consists of three different subunits: troponin T (TnT), troponin I (TnI) and troponin C (TnC). Each subunit is responsible for a part of troponin complex function. TnT is a tropomyosin-binding subunit which regulates the interaction of troponin complex with thin filaments; TnI inhibits ATP-ase activity of acto-myosin; TnC is a Ca2+ - binding subunit, playing the main role in Ca2+ dependent regulation of muscle contraction.
Keywords
Cardiac marker; Troponin; Troponin complex; Troponin C; Troponin I; Troponin T
Citations
Publication ()
Have you cited DAG-WT1155 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
