Troponin-ITC complex (≥80%)

Nature

Native

Tag/Conjugate

Unconjugated

Alternative Names

Cardiac Troponin C+I+T Complex Protein; Troponin Complex Protein; Cardiac Troponin C/I/T Protein

Purity

≥80% by SDS-PAGE

Format

Liquid

Concentration

Batch dependent - please inquire should you have specific requirements

Buffer

50 mM NaCI, 10 mM imidazole, 15 mM β-mercaptoethanol, 0.2 mM calcium chloride, pH 7.0

Preservative

0.025% Sodium Azide

Storage

Short Term (< 1 week): -20°C. Long Term: ≤-70°C. Avoid repeated freezing and thawing.

Antigen Description

Troponin complex is a heteromeric protein playing an important role in the regulation of skeletal and cardiac muscle contraction. Troponin complex consists of three different subunits troponin T (TnT), troponin I (TnI) and troponin C (TnC). Each subunit is responsible for a part of troponin complex function. TnT is a tropomyosin-binding subunit which regulates the interaction of troponin complex with thin filaments; TnI inhibits ATP-ase activity of acto-myosin; TnC is a Ca2+ - binding subunit, playing the main role in Ca2+ dependent regulation of muscle contraction.

Keywords

Cardiac Troponin C+I+T Complex Protein;Troponin Complex Protein;Cardiac Troponin C/I/T Protein