Lyophilized from 0.22 μm filtered solution in 2mM DTT, PBS, pH 7.2, 5% trehalose
Preservative
None
Storage
Store at -20°C
Introduction
S100A8/A9, also known as Calprotectin, is a heterodimeric protein that belongs to the family of low molecular weight, calcium binding S100 proteins with two EF-hand calcium binding domains. Calcium and zinc binding influences the S100A8/A9 conformation and oligomerization state, which includes the self-assembly into homo- and heterodimers and larger oligomers. S100A8/A9 is elevated in blood and other body fluids in many pathological conditions including rheumatoid arthritis, inflammatory bowel diseases, viral or microbial infections, and tumors. S100A8/A9 is identified as an endogenous activator of TLR4 and is involved in promoting the inflammatory response in infections.
Keywords
Calprotectin; S100A8/A9
Citations
Publication ()
Have you cited DAG-WT2154 in a publication? Let us know and earn a reward for your research.
My Review for Recombinant Human Calprotectin (S100A8&S100A9) [His]
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.