Recombinant Hepatitis B Virus Core Antigen

Product Overview

This antigen is a recombinant HBcAg with a polyspherical conformation. Can effectively capture the anti-HBAg antibody in the test sample. It has excellent specificity, sensitivity and stability.

Target

HBcAg

Nature

Recombinant

Molecular Weight

Monomer: 20KD; Spherical polymer: about 2200kD

Alternative Names

Hepatitis B Virus Core Antigen; HBcAg; HBV

Format

Liquid

Buffer

CBS, pH10.5

Preservative

None

Storage

Store at 2°C to 8°C.

Introduction

Hepatitis B Virus (HBV) infection inducesa disease state characterised by liver damage, inflammation and viralpersistence. Infection also increases the risk of hepatocellular carcinoma.HBV belongs to the Hepadnaviridae family of viruses. Its genome consists ofpartially double stranded circular DNA. The DNA is enclosed in anucleocapsid, or core antigen (HBcAg), which is surrounded by a sphericalenvelope (surface antigen or HBsAg). The core antigen shares its sequenceswith the e antigen (HBeAg) but no cross reactivity between the two proteinshas been observed. The HBV genome also encodes a DNA polymerase that alsoacts as a reverse transcriptase.

Keywords

Hepatitis B Virus Core Antigen; HBcAg; HBV