C-terminal 6xHis tagged HBcAg (HBV) protein (a.a. 1-149)
Nature
Recombinant
Tag/Conjugate
His
Purity
> 95%, based on SDS PAGE
Format
Each vial contains 100 μg of lyophilized protein in PBS with 8M Urea.
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
An antigen of the DNA core of the hepatitis B virus, indicating the presence of replicating hepatitis B virus. The nucleocapsid of the Hepatitis B virus (HBV) is extremely immunogenic. The icosahedral nucleocapsid is composed of 180 or 240 subunits of a 183-residue protein that is known as the HBV core (HBc) antigen (HBcAg). The subunits are clustered as dimers, producing spikes that protrude from the underlying shell domain, and contain the immunodominant loop of HBcAg. HBc antigen (HBcAg) capsids can activate naive B cells by cross-linking their surface receptors.
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