Product Overview
Recombinant HBcAg fused to a His tag containing the HBV core immunodominant region amino acids 1-186 was expressed in E. coli and purified by proprietary chromatographic technique.
Purity
> 90% pure as determined by 10% PAGE (Coomassie staining).
Buffer
25mM Tris-HCl pH-8.0, 1.5mM Urea and 50% glycerol.
Storage
2-8°C short term, -20°C long term
Introduction
HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious).
Keywords
Hepatitis B core antigen; HBcAg; Hepatitis B Core Antigen
Citations
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Yan, JB; Liu, XQ; et al. Enhancing the potency of HBV DNA vaccines using fusion genes of HBV-specific antigens and the N-terminal fragment of gp96. JOURNAL OF GENE MEDICINE 9:107-121(2007).
Evans, A; Riva, A; et al. Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion. HEPATOLOGY 48:759-769(2008).
COA
Certificate of Analysis
