Product Overview
Human C9 Protein
Tag/Conjugate
Unconjugated
Concentration
1.0 mg/ml (see Certificate of Analysis for actual concentration)
Buffer
10 mM sodium phosphate, 145 mM NaCl, pH 7.3
Storage
2-8°C short term, -20°C long term
Introduction
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
Antigen Description
Native human C9 is a naturally glycosylated (7.8%) protein composed of a single polypeptide chain. The molecular weight is 71,000 Da. C9 binds to the C5b-8 complex and forms the mature membrane attack complex (MAC) on cell membranes. Each pathway of compl
Keywords
C9; complement component 9; C9D; ARMD15; complement component C9;
Citations
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COA
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