Anti-GST tag antibody [Texas Red®]

Background Whether glutathione S-transferase (GST) null polymorphisms, namelyGSTM1null,GSTP1null andGSTT1null polymorphisms, influence the risk of coronary artery disease (CAD) or not remains unclear. Thus, the authors performed a meta-analysis to more robustly estimate associations betweenGSTnull polymorphisms and the risk of CAD by integrating the results of previous publications. Methods Medline, Embase, Wanfang, VIP and CNKI were searched comprehensively for eligible studies, and 45 genetic association studies were finally selected to be included in this meta-analysis. Results We found thatGSTM1null polymorphism was significantly associated with the risk of CAD in overall population (OR = 1.37,p = 0.003) and mixed population (OR = 1.61,p = 0.004),GSTP1null polymorphism was significantly associated with the risk of CAD in overall population (OR = 1.23,p = 0.03), whereasGSTT1null polymorphism was significantly associated with the risk of CAD in overall population (OR = 1.23,p = 0.02), Caucasians (OR = 1.23,p = 0.02) and East Asians (OR = 1.38,p < 0.0001). Conclusions This meta-analysis demonstrated thatGSTM1null,GSTP1null andGSTT1null polymorphisms were all significantly associated with an increased risk of CAD.

GST is a single and destination based tax which will be levied at the time of consumption of goods and services. It will be levied only on the additional value so that credit of inputs taxes already paid (at the time of purchase of inputs) can be availed. Thus, ultimate consumer will bear the GST that will be charged by the last dealer in supply chain, with set off benefits at all the previous stage. It has been three years since the inception of GST therefore; the study was conducted with an aim of assessing the level of knowledge about GST among respondents in Haldwani, Uttarakhand. Primary data for the study was collected with the help of well-structured questionnaire. Chi-square, mean, and standard deviation were utilized as tools for analysis. The analysis leads to the findings that 12 respondents have high level of knowledge about GST, 35 respondents have moderate level of knowledge and 13 respondents have low level of knowledge. Chi-square analysis leads to the findings that level of knowledge is independent of gender, age, educational status, and occupational status.