Molecular Weight
334.39 g/mol
Alternative Names
penicillin g; Benzylpenicillin; Benzylpenicillinic acid
Application Notes
Standards in ELISA
Introduction
Penicillin G is a broad-spectrum, beta-lactam naturally occurring penicillin antibiotic with antibacterial activity. Penicillin G binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and eventually causing cell lysis.
Keywords
Penicillin; Benzylpenicillin; Penicillin G
Citations
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Uyttebroek, AP; Sabato, V; et al. In Vitro Diagnosis of Immediate IgE-Mediated Drug Hypersensitivity Warnings and (Unmet) Needs. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA 34:681-+(2014).
Schummer, C; Schliemann, S; et al. Cutaneous manifestation of late-type syphilis. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 139:1883-1886(2014).