Molecular Weight
app. 65 kDa
Alternative Names
penicillin g; Benzylpenicillin; Benzylpenicillinic acid; Free penicillin II; Pencillin G
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Penicillin is a group of Beta-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. beta-lactam antibiotics work by inhibiting the formation of peptidoglycan cross-links in the bacterial cell wall, which results in cytolysis.
Antigen Description
Penicillin G, covalently linked to human serum albumin
Keywords
drug-HSA conjugate, drug-conjugate, penicillin G HSA conjugate
Citations
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Q & A
Q: Could you provide the average number or ratio of target molecules conjugated per one HSA molecule for each product?
A: Conjugation ratios on HSA are between 10-20 antibiotics/HSA.
Customer Reviews
Qiao, HL; Liu, JH; et al. Relationships between skin test, specific IgE and levels of cytokines in patients with penicillin allergy. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE 59:895-899(2005).
Karaseva, NA; Ermolaeva, TN; et al. Piezoelectric immunosensors for the detection of individual antibiotics and the total content of penicillin antibiotics in foodstuffs. TALANTA 120:312-317(2014).