General Notes
This product (Catalog No. DMAB-CPT984) is a rabbit-derived monoclonal antibody raised against mouse Mouse TIGIT. It has been affinity purified by Protein A. TIGIT (also called WUCAM, Vstm3, VSIG9) is a receptor of the Ig superfamily, which plays a critical role in limiting adaptive and innate immunity. TIGIT participates in a complex regulatory network involving multiple IRs (eg, CD96/TACTILE, CD112R/PVRIG), one competing costimulatory receptor (DNAM-1/CD226), and multiple ligands (eg, CD155 (PVR/NECL-5), CD112 (Nectin-2/PVRL2).
DMAB-CPT984 is suitable for use in Cytometric Bead Array (0.313-40 ng/mL) application.
DMAB-CPT984 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.