Synthetic peptide corresponding to a region within C terminal amino acids 169-218 (ALRIHSVEGD LRRKSAGQEE WSPSAPSPPG SCVQAEAAPA GLCGEQRGED) of Human TIGIT (NP_776160).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
TIGIT; T cell immunoreceptor with Ig and ITIM domains; V set and immunoglobulin domain containing 9; V set and transmembrane domain containing 3; VSIG9, VSTM3; T-cell immunoreceptor with Ig and ITIM domains; DKFZp667A205; FLJ39873; V-set and transmembrane
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Citations
Publication ()
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COA
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