Product Overview
HA1 (A/Vietnam/1203/2004) (H5N1) (AY651334, 1 a.a. - 345 a.a.) partial recombinant protein with His tag expressed in 293 cells.
Storage
2-8°C short term, -20°C long term
Introduction
Influenza A virus subtype H5N1, also known as "bird flu", A(H5N1) or simply H5N1, is a subtype of the influenza A virus which can cause illness in humans and many other animal species. A bird-adapted strain of H5N1, called HPAI A(H5N1) for "highly path
Antigen Description
Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. Hemagglutinin binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. It plays a major role in the determination of host range restriction and virulence and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
Keywords
Influenzavirus A; Influenza A virus; Influenza A virus H5N1; H5N1; IAV H5N1
Citations
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