Human Prealbumin (DAGC251)

Native Human Prealbumin from Human Plasma

Nature
Native
Tag/Conjugate
unconjugated
Molecular Weight
55 kDa
Alternative Names
Prealbumin; PAB; transthyretin; TTR; PALB
Procedure
None
Purity
> 96% (SDS-PAGE, dimer and tetramer may be observed)
Format
Lyophilized
Size
100ug, 1mg
Buffer
Lyophilized from 0.02 M ammonium bicarbonate. May contain traces of buffer salts.
Preservative
None
Storage
Store at 2-8°C
Reconstitution
Human Plasma
Ship
Cold pack
Introduction
Transthyretin (TTR or TBPA) is a transport protein in the serum and cerebrospinal fluid that carries the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. This is how transthyretin gained its name: transports thyroxine and retinol. The liver secretes transthyretin into the blood, and the choroid plexus secretes TTR into the cerebrospinal fluid.
Keywords
Prealbumin; PAB; transthyretin; TTR; PALB

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References


Gioeva, Z; Urban, P; et al. ATTR amyloid in the carpal tunnel ligament is frequently of wildtype transthyretin origin. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 20:1-6(2013).
KAMEKO, M; OTA, H; et al. DISTRIBUTION OF RETINOL-BINDING PROTEIN IN THE HUMAN DIGESTIVE-TRACT. VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY 61:315-322(1992).

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