General Notes
This product (Catalog No. DMAB-CBAS089) is a mouse-derived monoclonal antibody raised against human PARK7. It has been affinity purified by Protein A. PARK7, also known as DJ-1, is a gene that encodes the DJ-1 protein. This protein plays a crucial role in protecting cells, particularly brain cells, from oxidative stress and misfolded protein accumulation. Mutations in the PARK7 gene can lead to the early-onset form of Parkinson's disease, a neurodegenerative disorder characterized by the progressive loss of dopamine-producing neurons in the brain. Loss of functional DJ-1 protein due to PARK7 mutations impairs its ability to protect cells from oxidative stress and protein misfolding, ultimately leading to neuronal death and the motor symptoms associated with Parkinson's disease. The DJ-1 protein is also involved in various cellular processes, such as transcriptional regulation, RNA processing, and protein quality control, further highlighting its importance in maintaining neuronal health and function.
DMAB-CBAS089 is suitable for use in ELISA(Det) application.
DMAB-CBAS089 is supplied as a liquid formulation in Phosphate-buffered saline (PBS), carrier-free, with optional 0.09% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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