Anti-PARK7 (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

PARK7 (AAH08188, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLED AKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKG

Conjugate

Alternative Names

PARK7; parkinson protein 7; DJ1; DJ-1; HEL-S-67p; protein DJ-1; oncogene DJ1; epididymis secretory sperm binding protein Li 67p; Parkinson disease (autosomal recessive, early onset) 7;

Entrez Gene ID

UniProt ID

Antigen Description

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Pathway

Alpha-synuclein signaling; Parkinsons disease; Synaptic Vesicle Pathway;