Sample
Serum, plasma, tissue homogenates and other biological fluids
Intended Use
MECOM ELISA Kit allows for the in vitro quantitative determination of MECOM concentrations in serum, plasma, tissue homogenates and other biological fluids.
Storage
2-8 °C for 6 months
Precision
Intra-assay:CV<8%;
Inter-assay:CV<10%
Detection Range
78.125-5000pg/ml
Sensitivity
< 46.875pg/ml
Citations
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Bard-Chapeau, EA; Jeyakani, J; et al. Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:2168-2173(2012).
De Weer, A; Van der Meulen, J; et al. EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells. BRITISH JOURNAL OF HAEMATOLOGY 154:337-348(2011).