Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 80-109 of Human EVI1 (Q13465; NP_004982.2).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500.
Target
Alternative Names
MECOM; MDS1 and EVI1 complex locus; EVI1; MDS1; PRDM3; MDS1-EVI1; AML1-EVI-1; MDS1 and EVI1 complex locus protein EVI1; oncogene EVI1; zinc finger protein Evi1; AML1-EVI-1 fusion protein; MDS1 and EVI1 complex locus protein MDS1; myelodysplasia syndrome-a
EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. EVI1 may be involved in megakaryocytic differentiation.
Pathway
Chronic myeloid leukemia; MAPK signaling pathway; Pathways in cancer;
Citations
Publication ()
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COA
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