Product Overview
Recombinant Human T-cell surface glycoprotein CD5 is produced by Mammalian expression system and the target gene encoding Arg25-Pro372 is expressed with a 6His tag at C-terminus.
Molecular Weight
Mol Mass: 39.5 KDa
APMol Mass: 43-55 KDa
Endotoxin
< 1 EU/μg as determined by LAL test.
Alternative Names
CD5; T-cell surface glycoprotein CD5; Lymphocyte antigen T1; LEU1
Purity
>95% as determined by reducing SDS-PAGE
Buffer
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months.
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Introduction
The CD5 coreceptor is a cysteine-rich scavenger receptor family glycoprotein that is expressed constitutively on all T cells and a subset of B cells (B I a B cells). It is now generally accepted that the biologic role of CD5 is to regulate intracellular strength induced by antigen receptors in both T and B cells. The CD5 is a key regulator of immune tolerance and that alterations of its activity can promote development of autoreactivity.
Keywords
CD5; T-cell surface glycoprotein CD5; Lymphocyte antigen T1; LEU1
Citations
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