Magic™ Rabbit Anti-Human AHR Monoclonal antibody, clone 351436G5

Antibody Isotype

IgG

Clone

351436G5

Species Reactivity

Human

Immunogen

AHR fusion protein

Conjugate

Application Notes

We recommend the following antibodies for sandwich immunoassay (Capture - Detection):
DMAB-CPT1027 - DMAB-CPT1028
Cytometric Bead Array: 0.625-80 ng/mL

General Notes

This product (Catalog No. DMAB-CPT1027) is a rabbit-derived monoclonal antibody raised against human AHR. It has been affinity purified by Protein A. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter. AHR calculated molecular masses differ by <10%, compared with the apparent molecular masses predicted from SDS-PAGE for the two receptors (105 and 95 kDa, respectively).
DMAB-CPT1027 is suitable for use in Cytometric Bead Array (0.625-80 ng/mL) application.
DMAB-CPT1027 is supplied as a liquid formulation in PBS only. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Ah receptor; AHR; aryl hydrocarbon receptor; bHLHe76

Entrez Gene ID

UniProt ID