Synthetic peptide corresponding to residues near the N terminal of human aryl hydrocarbon receptor
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-03836) is a rabbit-derived IgG polyclonal antibody raised against human AHR. This antibody exhibits cross-reactivity with AHR from mouse. It has been affinity purified by protein A. The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. DPABH-03836 is suitable for use in IHC (1:50–1:200) application. DPABH-03836 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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