Specifications
Species Reactivity
Mouse, Rat
Immunogen
Rat GABA-A-R-Alpha4.
aa 410–450 (cytoplasmic C-terminus) of rat GABA-A-R-Alpha4
Applications
Application Notes
Suitable for use in IHC, ICC.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Target
Alternative Names
Gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor subunit alpha-4; Gabra4
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Roberts, DS; Raol, YH; et al. Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha 4 subunit expression (vol 102, pg 11894, 2005). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102:13351-13351(2005).
MCLEAN, PJ; FARB, DH; et al. MAPPING OF THE ALPHA(4) SUBUNIT GENE (GABRA4) TO HUMAN-CHROMOSOME-4 DEFINES AN ALPHA(2)-ALPHA(4)-BETA(1)-GAMMA(1) GENE-CLUSTER - FURTHER EVIDENCE THAT MODERN GABA(A) RECEPTOR GENE CLUSTERS ARE DERIVED FROM AN ANCESTRAL CLUSTER. GENOMICS 26:580-586(1995).
COA
Certificate of Analysis
