Specifications
Immunogen
A synthetic peptide of human GABRA4 is used for rabbit immunization.
Target
Alternative Names
GABRA4; gamma-aminobutyric acid (GABA) A receptor, alpha 4; gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor; alpha 4; GABA(A) receptor, alpha 4;
Product Background
Antigen Description
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Pathway
GABA A receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Morphine addiction, organism-specific biosystem.
Citations
Publication ()
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