Synthetic peptide within Human GABA A Receptor alpha 4 aa 356-386 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P48169
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Pathway
GABA A receptor activation; GABAergic synapse; Ion channel transport; Morphine addiction
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Agrawal, A; Pergadia, ML; et al. Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerstrom Test for Nicotine Dependence. ADDICTION 104:471-477(2009).
Paydar, A; Lee, B; et al. Extrasynaptic GABAA receptors in mediodorsal thalamic nucleus modulate fear extinction learning. MOLECULAR BRAIN 7:-(2014).
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