Anti-SYK Polyclonal Antibody (CABT-L2160) Knockout Validated

Rabbit Anti-Human SYK (Asp374~Asn635) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fragment corresponding to human SYK (Asp374~Asn635)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type 293T cell lysate. Lane 2: SYK knockout 293T cell lysate. Predicted MW: 69, 72kd, Observed MW: 69kd
Figure. Western Blot. Sample. Lane1: Mouse Spleen Tissue; Lane2: Rat Spinal Cord Tissue.

Target


Alternative Names
p72-Syk; Spleen tyrosine kinase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Alpha-synuclein signaling; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Atypical NF-kappaB pathway; B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; BCR signaling pathway; Cytokine Signaling in Immune system;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Rafnar, T; Peebles, RS; et al. Stimulation of the high-affinity IgE receptor results in the tyrosine phosphorylation of a 60 kD protein which is associated with the protein-tyrosine kinase, Csk. MOLECULAR IMMUNOLOGY 35:249-257(1998).
Nakashima, K; Kokubo, T; et al. A novel Syk kinase-selective inhibitor blocks antigen presentation of immune complexes in dendritic cells. EUROPEAN JOURNAL OF PHARMACOLOGY 505:223-228(2004).

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