Product Overview
Blocking/Immunizing peptide for anti-Spleen tyrosine kinase/SYK antibody
Target
Spleen tyrosine kinase / SYK
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Function
ATP binding; integrin binding; non-membrane spanning protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein domain specific binding; protein kinase activity; protein kinase bi
Synonyms
SYK; spleen tyrosine kinase; tyrosine-protein kinase SYK; p72-Syk; FLJ25043; FLJ37489; DKFZp313N1010;
Citations
Publication ()
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