Anti-PYGL Polyclonal Antibody (CABT-L2013) Knockout Validated

Rabbit Anti-Human PYGL (Thr341~Gly509) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Rat
Immunogen
Recombinant fragment corresponding to human PYGL (Thr341~Gly509)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hepg2 cell lysate. Lane 2: PYGL knockout Hepg2 cell lysate. Predicted MW: 97kDa, Observed MW: 100kDa
Western Blot. Sample. Human HepG2 cell lysate.
Western Blot. Sample. Rat Liver lysate.
Western Blot. Sample. Rat Skin lysate.

Target


Alternative Names
GPLL; GPBB; Hers Disease; Glycogen Storage Disease Type VI
Entrez Gene ID
UniProt ID

Product Background


Pathway
Disease; Glucose metabolism; Glycogen Metabolism; Glycogen breakdown (glycogenolysis); Glycogen storage diseases; Insulin signaling pathway; Metabolic pathways; Metabolism;

Citations


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References


Ballester, J; Fernandez-Novell, JM; et al. Evidence for a functional glycogen metabolism in mature mammalian spermatozoa. MOLECULAR REPRODUCTION AND DEVELOPMENT 56:207-219(2000).
HESPELING, U; PUSCHEL, GP; et al. STIMULATION OF GLYCOGEN-PHOSPHORYLASE IN RAT HEPATOCYTES VIA PROSTANOID RELEASE FROM KUPFFER CELLS BY RECOMBINANT RAT ANAPHYLATOXIN C5A BUT NOT BY NATIVE HUMAN C5A IN HEPATOCYTE KUPFFER CELL COCULTURES. FEBS LETTERS 372:108-112(1995).

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