Anti-PYGB Polyclonal Antibody (CABT-L2116) Knockout Validated

Rabbit Anti-Human PYGB (Pro477~Glu731) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human PYGB (Pro477~Glu731)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: PYGB knockout A549 cell lysate. Predicted MW: 97kd, Observed MW: 100kd
Western Blot. Sample. Human A549 cell lysate.
Western Blot. Sample. Human Lung lysate.
Western Blot. Sample. Mouse Cerebrum lysate.

Target


Alternative Names
GPBB
Entrez Gene ID
UniProt ID

Product Background


Pathway
Disease; Glucose metabolism; Glycogen Metabolism; Glycogen breakdown (glycogenolysis); Glycogen storage diseases; Insulin signaling pathway; Metabolic pathways; Metabolism;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Philips, KB; Kurtoglu, M; et al. Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose. CANCER CHEMOTHERAPY AND PHARMACOLOGY 73:349-361(2014).
Rich, SS; Goodarzi, MO; et al. A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). DIABETOLOGIA 52:1326-1333(2009).

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