Anti-PDCD1 Polyclonal Antibody (CABT-L2060) Knockout Validated

Rabbit Anti-Human PDCD1 (Leu41~Ala132) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Pig
Immunogen
Recombinant fragment corresponding to human PDCD1 (Leu41~Ala132)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml; 1:200-900
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: PDCD1 knockout Jurkat cell lysate. Predicted MW: 32kDa, Observed MW: 32kDa
Western Blot. Sample. Porcine Lymph node lysate.

Target


Alternative Names
CD279; PD1; SLEB2; HPD1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Cell adhesion molecules (CAMs); Costimulation by the CD28 family; Immune System; PD-1 signaling; T cell receptor signaling pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Wang, JA; Okazaki, I; et al. PD-1 deficiency results in the development of fatal myocarditis in MRL mice. INTERNATIONAL IMMUNOLOGY 22:443-452(2010).
Goere, D; Flament, C; et al. Potent Immunomodulatory Effects of the Trifunctional Antibody Catumaxomab. CANCER RESEARCH 73:4663-4673(2013).

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