Anti-KPNa2 Polyclonal Antibody (CABT-L2028) Knockout Validated

Rabbit Anti-Human KPNa2 (Ala157~Gln412) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human KPNA2 (Ala157~Gln412)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 1-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type HepG2 cell lysate. Lane 2: KPNa2 knockout HepG2 cell lysate. Predicted MW: 58kDa, Observed MW: 58kDa
Figure. Western Blot. Sample. Lane1: Human HepG2 Cells; Lane2: Human 293T Cells; Lane3: Human Raji Cells.

Target


Alternative Names
IPOA1; QIP2; RCH1; SRP1alpha; RAG Cohort 1; Importin Alpha 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Antiviral mechanism by IFN-stimulated genes; Cytokine Signaling in Immune system; ISG15 antiviral mechanism; Immune System; Influenza A; Interferon Signaling; Regulation of cytoplasmic and nuclear SMAD2/3 signaling; Role of Calcineurin-dependent NFAT signaling in lymphocytes;

Citations


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References


Dankof, A; Fritzsche, FR; et al. KPNA2 protein expression in invasive breast carcinoma and matched peritumoral ductal carcinoma in situ. VIRCHOWS ARCHIV 451:877-881(2007).
Zhang, CB; Kallakury, BV; et al. The significance of TNFAIP8 in prostate cancer response to radiation and docetaxel and disease recurrence. INTERNATIONAL JOURNAL OF CANCER 133:31-42(2013).

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