Anti-CARD9 Polyclonal Antibody (CABT-L2269) Knockout Validated

Rabbit Anti-Human CARD9 (Asp26~Leu283) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human CARD9 (Asp26~Leu283)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type PC3 cell lysate. Lane 2: CARD9 knockout PC3 cell lysate. Predicted MW: 62, 56, 43kd, Observed MW: 50kd
Western Blot. Sample. Human HepG2 cell lysate.
Western Blot. Sample. Human HL60 cell lysate.
Western Blot. Sample. Human PC3 cell lysate.
Western Blot. Sample. Human Serum;

Target


Alternative Names
CARD9
Entrez Gene ID
UniProt ID

Product Background


Pathway
Immune System; Innate Immune System; NOD pathway; NOD-like receptor signaling pathway; NOD1/2 Signaling Pathway; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways; Tuberculosis;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Gabrielli, E; Pericolini, E; et al. Antibody Constant Region Peptides Can Display Immunomodulatory Activity through Activation of the Dectin-1 Signalling Pathway. PLOS ONE 7:-(2012).
Mezger, M; Kneitz, S; et al. Proinflammatory response of immature human dendritic cells is mediated by Dectin-1 after exposure to Aspergillus fumigatus germ tubes. JOURNAL OF INFECTIOUS DISEASES 197:924-931(2008).

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