Human CARD9 blocking peptide (CDBP0681)

Synthetic Human CARD9 blocking peptide for BL

Product Overview
CARD9 ( C - term ) peptide ( human )
Target
CARD 9
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Procedure
None
Concentration
0.2 mg/ml
Size
50 μg
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Preservative
0.02% Sodium Azide
Storage
Upon receipt - Keep as concentrated solution. Aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
UniProt ID
Antigen Description
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Function
CARD domain binding; protein homodimerization activity;
Synonyms
CARD9; caspase recruitment domain family, member 9; caspase recruitment domain-containing protein 9; CANDF2; hCARD9;

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References


Yoshiyuki, A; et al. Role of the 1,3-beta-D-glucan receptor Dectin-1 in fungal infection and activation of innate and anti-tumor immunity. TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 19:195-207(2007).
Lilic, D; et al. Unravelling fungal immunity through primary immune deficiencies. CURRENT OPINION IN MICROBIOLOGY 15:420-426(2012).

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