Human CARD9 blocking peptide (DAG-P0280)

Synthetic Human CARD9 blocking peptide for BL Datasheet

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Specificity
Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Nature
Synthetic
Tag/Conjugate
Unconjugated
Sequence Similarities
Contains 1 CARD domain.
Cellular Localization
Cytoplasm.
Format
Liquid
Buffer
PBS with 0.1% BSA 0.02% sodium azide pH7.2
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. PBS with 0.1% BSA 0.02% sodium azide pH7.2
UniProt ID
Antigen Description
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]
Function
CARD domain binding; protein homodimerization activity;
Synonyms
CARD9; caspase recruitment domain family, member 9; CANDF2; hCARD9; caspase recruitment domain-containing protein 9;

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