Anti-AIF Polyclonal Antibody (CABT-L2123) Knockout Validated

Rabbit Anti-Human AIF (Gly103~Lys322) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Pig
Immunogen
Recombinant fragment corresponding to human AIFM1 (Gly103~Lys322)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: AIF knockout A549 cell lysate. Predicted MW: 26~35, 66kd, Observed MW: 66kd
Figure. Western Blot. Sample. Lane1: Porcine Liver Tissue; Lane2: Porcine Heart Tissue; Lane3: Human Hela Cells; Lane4: Human A549 Cells.

Target


Alternative Names
PDCD8; Programmed Cell Death protein 8; Apoptosis-inducing factor 1, mitochondrial
UniProt ID

Product Background


Pathway
Apoptosis; Apoptosis Modulation by HSP70; Ceramide signaling pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Dam, AD; Mitchell, AS; et al. Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:3426-3435(2013).
Su, Y; Arbelaez, AM; et al. Noninvasive estimation of the arterial input function in positron emission tomography imaging of cerebral blood flow. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 33:115-121(2013).

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