Anti-ACAT1 Polyclonal Antibody (CABT-L2290) Knockout Validated

Rabbit Anti-Human ACAT1 Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant Human ACAT1
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: ACAT1 knockout A549 cell lysate. Predicted MW: 17, 45kd, Observed MW: 44kd

Target


Alternative Names
THIL; ACAT; T2; MAT; Acetoacetyl Coenzyme A Thiolase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Branched-chain amino acid catabolism; Butanoate metabolism; C5 isoprenoid biosynthesis, mevalonate pathway; Carbon metabolism; Fatty Acid Beta Oxidation; Fatty acid degradation; Fatty acid metabolism; Fatty acid, triacylglycerol, and ketone body metabolism;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Sakashita, N; Miyazaki, A; et al. Acyl-coenzyme A : cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: In vivo and in vitro studies. LABORATORY INVESTIGATION 83:1569-1581(2003).
Lee, RG; Willingham, MC; et al. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. JOURNAL OF LIPID RESEARCH 41:1991-2001(2000).

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