Product Overview
TACI peptide ( human )
Tag/Conjugate
Unconjugated
Application Notes
stable for one year.
Buffer
Preservative: 0.02% Sodium Azide; Constituents: 0.1% BSA, PBS. pH 7.2
Preservative
0.02% Sodium Azide
Antigen Description
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Function
protein binding; receptor activity;
Synonyms
TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor;
Citations
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Wang, HY; Gopalan, V; et al. A Custom 148 Gene-Based Resequencing Chip and the SNP Explorer Software: New Tools to Study Antibody Deficiency. HUMAN MUTATION 31:1080-1088(2010).
Lee, JJ; Ozcan, E; et al. Transmembrane activator and calcium-modulator and cyclophilin ligand interactor mutations in common variable immunodeficiency. CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY 8:520-526(2008).