Mouse myeloma cell line NS0-derived recombinant mouse TACI/TNFRSF13B. Phe5-Thr129 Accession Number Q9ET35
Conjugate
Unconjugated
Applications
Application Notes
Western Blot: 1 μg/mL; Flow Cyt: 2.5 μg/106 cells; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4167 - DPABY-617
Target
Alternative Names
TNFRSF13B; tumor necrosis factor receptor superfamily, member 13b; Taci; 1200009E08Rik; tumor necrosis factor receptor superfamily member 13B; transmembrane activator and CAML interactor; transmembrane activator and calcium-modulating and cyclophilin liga
TACI, transmembrane activator and CAML-interactor, is a member of the TNF receptor superfamily (TNFRSF). Within the TNFRSF, it shares the highest homology with BCMA. TACI and BCMA both bind APRIL and BLyS/BAFF, members of the TNF superfamily. TACI is expressed on the cell surface of B cells and activated, but not resting, T cells. Human and mouse TACI share 54% amino acid sequence identity.
Pathway
Cytokine-cytokine receptor interaction; Intestinal immune network for IgA production; Primary immunodeficiency;
Citations
Publication ()
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COA
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