Human SRCAP blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-SRCAP antibody

Target

SRCAP

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

10847

UniProt ID

Q6ZRS2

Antigen Description

This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]

Function

ATP binding; DNA binding; helicase activity; histone acetyltransferase activity; transcription coactivator activity;

Synonyms

SRCAP; Snf2-related CREBBP activator protein; EAF1; FLHS; SWR1; DOMO1; helicase SRCAP; domino homolog 2; Snf2-related CBP activator protein; Swi2/Snf2-related ATPase homolog, domino homolog 1;