Recombinant protein corresponding to amino acids of human SRCAP. The sequence is AQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAG SIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTS EELTEAKTPTSS
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:10-1:20; IF: 1-4 μg/mL. & The optimal working dilution should be determined by the end user.
This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features.
Citations
Publication ()
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