Recombinant protein corresponding to amino acids of human SRCAP. The sequence is AQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAG SIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTS EELTEAKTPTSS
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:10-1:20; IF: 1-4 μg/mL. & The optimal working dilution should be determined by the end user.
This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Deal, RB; Topp, CN; et al. Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z. PLANT CELL 19:74-83(2007).
Okazaki, N; Ikeda, S; et al. The novel protein complex with SMARCAD1/KIAA1122 binds to the vicinity of TSS. JOURNAL OF MOLECULAR BIOLOGY 382:257-265(2008).
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COA
Certificate of Analysis
